05/23/2024
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Recent Advances in High Throughput Experimentation (HTE) and Flow Chemistry
In this webinar, we will present the details of using high throughput experimentation (HTE) to identify reaction conditions for challenging transformations, giving access to a diverse array of medicinal chemistry targets. In parallel to using the conventional batch reactions to synthesize these targets, we also incorporate flow chemistry into the early phase helping reaction up-scaling as well as solving specific chemical problems. Case studies will be provided for both topics. -
Strategies for Screening and Characterizing Targeted Covalent Inhibitors
With advancements in drug design, there is resurging interest in drugs that form covalent bonds with their targets, often referred to as targeted covalent inhibitors (TCIs). In this webinar, experts discuss innovative approaches to screen for covalent binders, strategies for the synthesis of covalent warheads, and assays to optimize the ADME/DMPK properties of these molecules.
This webinar offers a comprehensive perspective on strategies that are crucial for accelerating research focused on covalent drug discovery. -
Emerging Modalities in Drug Discovery
In this webinar, we will present the latest advances and challenges facing researchers focused on new and emerging modalities in drug discovery. Topics will include targeted protein degradation, targeted covalent inhibitors, and nucleic acid therapeutics. Our expert speaker, Dr. Tao Guo, will discuss solutions for addressing the complexities in designing, synthesizing, and optimizing these molecules, with an added focus on the special modifications and delivery systems needed for siRNAs and ASOs.