Targeted Protein Degraders: Trends, Challenges, and Solutions

Targeted Protein Degraders: Trends, Challenges, and Solutions

Since 2016, WuXi AppTec has built a comprehensive discovery platform focused on Targeted Protein Degraders (TPDs). Our platform enables research teams to investigate the complete TPD functional cycle, from binary and ternary complex formation and protein ubiquitination to degradation. Our end-to-end services encompass over 20 assay technologies, 10+ types of TPD molecules, and one-stop screening for proteins of interest (POI) and linkers using a bifunctional DNA-encoded library.

 

 

 

 

 

CAPABILITIES

Library

Targeted Protein Degrader

Flow Chemistry

Reaction Condition Screening

Computer-aided Drug Design

Bio-Transformation

Analysis & Purification

Chemistry Synthesis

How can we help?

Get in touch with an expert.

Contact us