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Flow Chemistry Service

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Flow Chemistry – a better solution for safe, scalable, and efficient process

Take advantage of the numerous benefits of flow chemistry with a full-range services from condition screening to reaction up-scaling.

Service Highlights

Dedicated flow chemistry teams at numerous global sites
Special team for in-house catalyst development supporting flow hydrogenation
Full experience from parameter optimization to reaction up-scaling
Support both Medchem FTE and FFS projects
30,000+ reactions as of end of 2024-Q1
>95% Success rate
Experience with a wide scale of reactions from mg to kg
Broad temperature window from -78 ℃ to 300 ℃
Flow rate range from 0.05 mL/min to 500 mL/min
Up to four independently controlled reagent pumps
Quick turnaround time for condition screening within 2 days
More than 10 different continuous reaction systems including Corning and Vapourtec flow reactors

Reaction Types
- Photochemistry
- Hydrogenation
- Metallation reactions
- Nitration
- Diazotization
- High temperature reactions
- Hydride reduction
- Oxidation
- Halogenation
- Cross-coupling reactions

Instruments

Vapourtec flow system R series
- Flexible, precise and automatable
- Best in class performance
- Ideal for Medchem and process research
- Easy to set up and use
- Versatile and robust pumps
- Wide range of reaction conditions possible
- Cited in over 600 peer reviewed publications
- A proven design with over 400 installations worldwide

Corning flow system
- 1~5 kg production per day
- Outstanding mixing and heat exchange
- Low internal volume
- High residence time
- High chemical durability
- Flow rate range of 5 mL/min to 50 mL/min
- Broad temperature range, from -60 to 200 ℃
- Pressure up to 1.8 Mpa

Oushisheng flow hydrogenation system
- 2~5 kg production per day
- Broad temperature range, from r.t. to 200 ℃
- Catalyst diameter, from 0.2-2 mm
- Flow rate range of 5 mL/min to 50 mL/min
- Pressure up to 10 MPa

Flow Chemistry Service from Condition Screening to Scale Up

Condition Screening
- Photo reactor
Development
- Vapourtec flow reactor
Scale up
- 365-850 nm LED flow reactor