Research Chemistry
Services

Flow Chemistry

Home > Technology Platform

Flow Chemistry – a better solution for safe, scalable, and efficient process

Take advantage of the numerous benefits of flow chemistry with a full-range services from condition screening to reaction up-scaling.

Service Highlights

Dedicated flow chemistry teams at 5 domestic sites
Technical unit of catalyst development for hydrogenation in flow
Technical unit of engineering
Full experience from parameter optimization to reaction up-scaling
Daily support to all FTE and FFS projects
65,000+ reactions finished by 2024-Q3
>95% success rate
Experience with a wide scale of reactions from mg to kg
1-2 days of cycle time for product delivery in early phase
Seamless transfer to late phase development and manufacturing

Reaction Types
- Photochemistry
- Hydrogenation
- Metalation
- Nitration
- Diazotization
- Oxidation
- Reduction
- High temperature
- Cross-coupling

Instruments

Vapourtec flow system R series
- Flexible, precise and automatable
- Best in class performance
- Ideal for Medchem and process research
- Easy to set up and use
- Versatile and robust pumps
- Wide range of reaction conditions possible
- Cited in over 600 peer reviewed publications
- A proven design with over 400 installations worldwide

Corning flow system
- 1~5 kg production per day
- Outstanding mixing and heat exchange
- Low internal volume
- High residence time
- High chemical durability
- Flow rate range of 5 mL/min to 50 mL/min
- Broad temperature range, from -60 to 200 ℃
- Pressure up to 1.8 Mpa

Oushisheng flow hydrogenation system
- 2~5 kg production per day
- Broad temperature range, from r.t. to 200 ℃
- Catalyst diameter, from 0.2-2 mm
- Flow rate range of 5 mL/min to 50 mL/min
- Pressure up to 10 MPa

Flow Chemistry Service from Condition Screening to Scale Up

Condition Screening
- Photo reactor
Development
- Vapourtec flow reactor
Scale up
- 365-850 nm LED flow reactor