WuXi Biologics
Offering End-to-End Solutions
Research Chemistry
Services
Flow Chemistry
Flow Chemistry – a better solution for safe, scalable, and efficient process
Take advantage of the numerous benefits of flow chemistry with a full-range services from condition screening to reaction up-scaling.
Service Highlights
- Dedicated flow chemistry teams at numerous global sites
- Special team for in-house catalyst development supporting flow hydrogenation
- Full experience from parameter optimization to reaction up-scaling
- Support both Medchem FTE and FFS projects
- 30,000+ reactions as of end of 2024-Q1
- >95% Success rate
- Experience with a wide scale of reactions from mg to kg
- Broad temperature window from -78 ℃ to 300 ℃
- Flow rate range from 0.05 mL/min to 500 mL/min
- Up to four independently controlled reagent pumps
- Quick turnaround time for condition screening within 2 days
- More than 10 different continuous reaction systems including Corning and Vapourtec flow reactors
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Reaction Types
- Photochemistry
- Hydrogenation
- Metalation
- Nitration
- Diazotization
- Oxidation
- Reduction
- High temperature
- Cross-coupling
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Instruments
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Vapourtec flow system R series
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- Flexible, precise and automatable
- Best in class performance
- Ideal for Medchem and process research
- Easy to set up and use
- Versatile and robust pumps
- Wide range of reaction conditions possible
- Cited in over 600 peer reviewed publications
- A proven design with over 400 installations worldwide
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Corning flow system
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- 1~5 kg production per day
- Outstanding mixing and heat exchange
- Low internal volume
- High residence time
- High chemical durability
- Flow rate range of 5 mL/min to 50 mL/min
- Broad temperature range, from -60 to 200 ℃
- Pressure up to 1.8 Mpa
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Oushisheng flow hydrogenation system
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- 2~5 kg production per day
- Broad temperature range, from r.t. to 200 ℃
- Catalyst diameter, from 0.2-2 mm
- Flow rate range of 5 mL/min to 50 mL/min
- Pressure up to 10 MPa
Flow Chemistry Service from Condition Screening to Scale Up
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Condition Screening
- Photo reactor
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Development
- Vapourtec flow reactor
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Scale up
- 365-850 nm LED flow reactor