Discovery Process Chemistry

Overview

We bridge discovery chemistry to process chemistry by providing research services in rapid scale up and condition and process optimization.

 

  • Strong capability in new route scouting and process optimization, enabling shortened discovery research cycle times
  • Isolation, characterization, synthesis and control of impurities in process chemistry research and development
  • Validation of synthetic and analytical protocols
  • Stress test and safety evaluation
  • Smooth tech-pack and know-how knowledge transfer
  • Fast delivery of targets and supply of key intermediates and building blocks
  • Comprehensive platforms (e.g. photochemistry, flow chemistry, biocatalysis) to support fast and productive DPC work

 

 

Walk–in hoods  /  Large scale reactor  /  Large scale purification  /  Flow chemistry reactors

  • Process Safety Assessment Lab

    • Support desired reaction and secondary reaction
    • DSC, TGA, C80, RC1, TSU, ARC
    • Thermal screening and reaction characterization
  • OEB-4 Kilo Lab

    • OEL: 1 ~ 10 μg/m3
    • Every batch ≤ 3.0 kg
    • Low vacuum applied
  • GLP Analytical Lab

    • Regulated analytical services
    • NMR, LCMS, HPLC, GC, KF, HRMS
    • XRPD/XRSD, TGA, DSC, ICP-MS, AAS

CAPABILITIES

Library

Targeted Protein Degrader

Flow Chemistry

Reaction Condition Screening

Computer-aided Drug Design

Bio-Transformation

Analysis & Purification

Chemistry Synthesis